Description

Dapsone-13C12 is a stable isotope-labeled analog of the pharmaceutical compound Dapsone, where twelve carbon atoms are replaced with the carbon-13 isotope. This product is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is a critical material for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics industries who require precise quantification of Dapsone and its metabolites.

Application

• Quantitative Bioanalysis: Serves as an internal standard in LC-MS/MS and GC-MS methods for the precise measurement of Dapsone in biological matrices such as plasma, serum, and urine.
• Pharmacokinetic & Metabolite Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Pharmaceutical Quality Control: Used in assay development and validation to ensure the potency and purity of Dapsone-containing drug products.
• Forensic & Doping Control: Facilitates reliable identification and quantification of Dapsone in forensic toxicology and anti-doping analyses.
• Method Development & Validation: A key tool for developing robust, sensitive, and specific analytical methods compliant with regulatory guidelines (e.g., FDA, EMA).
• Stable Isotope Dilution Assays: The gold-standard technique for achieving maximum accuracy in complex sample analysis, correcting for matrix effects and instrument variability.

Basic Information

Product Name	Dapsone-13C12
CAS No.	1632119-29-9
Molecular Formula	13C12H12N2O2S
Molecular Weight	~252.3 (based on 13C substitution)
Synonyms	4,4'-Sulfonylbis[13C6]aniline; 4,4'-Diaminodiphenyl sulfone-13C12; DDS-13C12; Diaphenylsulfone-13C12; Avlosulfon-13C12; [13C12]-Dapsone; [U-13C12]-Dapsone; 13C12 Labeled Dapsone
EINECS	Contact for details

Quality Control

Our Dapsone-13C12 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity, which is critical for reliable analytical performance. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), and confirmation of structure (by NMR and MS). We adhere to industry best practices to support research requiring GMP/GLP compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (by NMR)	Conforms
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.