Description

2-(Diphenylphosphino)-n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-Benzamide CAS NO 1630973-03-3 is a sophisticated chiral organophosphorus ligand derived from cinchona alkaloid architecture. This compound matters for its exceptional ability to induce stereoselectivity in transition metal-catalyzed reactions, a critical factor in synthesizing high-value enantiomerically pure intermediates. Pharmaceutical research and fine chemical manufacturers need it for developing advanced active pharmaceutical ingredients (APIs) and specialty chemicals where precise spatial orientation of molecules is paramount.

Application

• Asymmetric Catalysis: A key chiral ligand for enantioselective hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Synthesis: Critical for the production of single-enantiomer drug candidates and complex chiral molecules in medicinal chemistry.
• Fine Chemical Manufacturing: Enables the synthesis of enantiomerically pure agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: Used in method development and discovery chemistry for novel catalytic processes.
• Material Science: Potential applications in creating chiral polymers or advanced materials with specific optical properties.

Basic Information

Product Name	2-(Diphenylphosphino)-n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-Benzamide
CAS No.	1630973-03-3
Molecular Formula	C40H37N3O2P
Molecular Weight	622.71 g/mol
Synonyms	2-(Diphenylphosphino)-N-[(8α,9S)-6'-methoxycinchonan-9-yl]benzamide; (8α,9S)-N-[2-(Diphenylphosphino)benzoyl]-6'-methoxycinchonan-9-amine; Cinchona Alkaloid-Derived Phosphine Ligand; Chiral Diphosphine Ligand Analog; P,N-Ligand; CAS 1630973-03-3
EINECS	Contact for details

Quality Control

Our 2-(Diphenylphosphino)-n-[(8α,9S)-6'-Methoxycinchonan-9-Yl]-Benzamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.