Description

5-(2-Bromoethyl)-1,3-Difluoro-2-Methoxybenzene is a versatile and high-value halogenated aromatic building block, specifically engineered for advanced organic synthesis. Its molecular structure, featuring a bromoethyl side chain and difluoro-methoxy substitution pattern, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates where the difluoro-methoxy group can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromoethyl moiety serves as a reactive handle for further functionalization to create compounds with specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorine-based organic electronic materials, contributing to the development of displays and lighting technologies.
• Cross-Coupling Reactions: The bromine atom is an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira), enabling the construction of complex biaryl and conjugated systems.
• Ligand & Catalyst Development: Utilized in the synthesis of specialized ligands for catalysis, where the methoxy and fluorine groups can fine-tune electronic properties and metal coordination.
• Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of novel aromatic compounds for screening.

Basic Information

Product Name	5-(2-Bromoethyl)-1,3-Difluoro-2-Methoxybenzene
CAS No.	1630906-97-6
Molecular Formula	C9H9BrF2O
Molecular Weight	251.07 g/mol
Synonyms	1-Bromo-2-(2,6-difluoro-3-methoxyphenyl)ethane; 2-(2-Bromoethyl)-1,3-difluoro-4-methoxybenzene; 2,6-Difluoro-3-methoxy-β-bromoethylbenzene; 5-(2-Bromoethyl)-2,6-difluoroanisole; 1,3-Difluoro-2-methoxy-5-(2-bromoethyl)benzene; Benzene, 5-(2-bromoethyl)-1,3-difluoro-2-methoxy-
EINECS	Contact for details

Quality Control

Our 5-(2-Bromoethyl)-1,3-Difluoro-2-Methoxybenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.