Description

(4-Chloro-2-Fluoro-6-Methoxyphenyl)Boronic Acid is a high-purity, functionalized boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of the chloro-fluoro-methoxy phenyl moiety can modulate biological activity.
• Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs or organic photovoltaics, due to its ability to form conjugated systems.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and sensors that leverage boronic acid's affinity for diols, useful in carbohydrate recognition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in custom synthesis projects requiring specific, high-value aryl boronic acids.

Basic Information

Product Name	(4-Chloro-2-Fluoro-6-Methoxyphenyl)Boronic Acid
CAS No.	1628684-10-5
Molecular Formula	C7H7BClFO3
Molecular Weight	203.39 g/mol
Synonyms	4-Chloro-2-fluoro-6-methoxybenzeneboronic acid; (4-Chloro-2-fluoro-6-methoxyphenyl)boronic acid; 2-Fluoro-4-chloro-6-methoxyphenylboronic acid; B-(4-Chloro-2-fluoro-6-methoxyphenyl)boronic acid; 4-Chloro-2-fluoro-6-methoxybenzeneboronic Acid; (4-Chloro-2-fluoro-6-methoxyphenyl)boronic acid, 95%; 1628684-10-5
EINECS	Contact for details

Quality Control

Our (4-Chloro-2-Fluoro-6-Methoxyphenyl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.