Description

tert-Butyl 6-Methyl-2,6-Diazaspiro[3.3]heptane-2-carboxylate is a high-value, spirocyclic building block and protected amine intermediate of significant interest in modern synthetic chemistry. Its rigid, three-dimensional structure and dual nitrogen functionality make it a critical scaffold for constructing complex molecules with improved pharmacological properties. This compound is primarily utilized by pharmaceutical research and development organizations engaged in discovering new therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its spirocyclic constraint, which can enhance potency, selectivity, and metabolic stability.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Incorporated into tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or insecticides with new modes of action.
• Academic & Contract Research: Employed in universities and CROs for methodological development and the synthesis of novel chemical libraries.

Basic Information

Product Name	tert-Butyl 6-Methyl-2,6-Diazaspiro[3.3]heptane-2-carboxylate
CAS No.	1628604-98-7
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-methyl-, 1,1-dimethylethyl ester; 6-Methyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester; tert-Butyl 6-methyl-2,6-diazaspiro[3.3]heptane-2-carboxylate; 2-(tert-Butoxycarbonyl)-6-methyl-2,6-diazaspiro[3.3]heptane; Boc-6-Me-2,6-diazaspiro[3.3]heptane; N-Boc-6-methyl-2,6-diazaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Methyl-2,6-Diazaspiro[3.3]heptane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support research and regulatory filings. We can supply material compliant with ICH guidelines for impurity profiling upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.