Description

2-(4-Chloro-3-Fluoro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific halogenated aryl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Development: Employed in process chemistry for scaling up the production of fine chemicals and specialty materials.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and catalysis studies within university and industrial laboratories.

Basic Information

Item	Details
Product Name	2-(4-Chloro-3-Fluoro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1628524-83-3
Molecular Formula	C13H17BClFO3
Molecular Weight	285.53 g/mol
Synonyms	4-Chloro-3-fluoro-2-methoxyphenylboronic acid pinacol ester; (4-Chloro-3-fluoro-2-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-4-chloro-3-fluorophenylboronic acid pinacol ester; 4-Chloro-3-fluoro-2-methoxybenzeneboronic acid pinacol ester; Pinacol (4-chloro-3-fluoro-2-methoxyphenyl)boronate; CAS 1628524-83-3
EINECS	Contact for details

Quality Control

Every batch of our 2-(4-Chloro-3-Fluoro-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure the highest standards of purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area Percent)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.