Description

1-(4-Borono-2-Fluorophenyl)Cyclopropane-1-Carboxylic Acid is a high-value, multifunctional organic building block containing both a boronic acid and a carboxylic acid functional group. This compound is critical for modern synthetic chemistry, particularly in cross-coupling reactions and the development of complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl motifs found in numerous drug candidates.
• Protease Inhibitor Synthesis: Used in the research and development of protease inhibitors, including potential antiviral and anticancer agents.
• Agrochemical Development: Serves as a building block for novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Bioconjugation & Labeling: The boronic acid group allows for selective conjugation with diols, useful in sensor development and biochemical probes.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and medicinal chemistry within academic and CRO laboratories.

Basic Information

Product Name	1-(4-Borono-2-Fluorophenyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1628507-86-7
Molecular Formula	C10H10BFO4
Molecular Weight	224.00 g/mol
Synonyms	2-Fluoro-4-(1-carboxycyclopropyl)phenylboronic acid; 4-Borono-2-fluoro-1-(1-carboxycyclopropyl)benzene; 1-Carboxy-1-(4-borono-2-fluorophenyl)cyclopropane; (4-Borono-2-fluorophenyl)cyclopropanecarboxylic acid; B-[2-Fluoro-4-(1-carboxycyclopropyl)phenyl]boronic acid; 1-(4-Boronophenyl)-2-fluorocyclopropane-1-carboxylic acid (isomer); FC-B(OH)2-Ph-cyclopropane-COOH
EINECS	Contact for details

Quality Control

Our production of 1-(4-Borono-2-Fluorophenyl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.