Description

1-(Trifluoromethyl)Cyclopropane-1-Carboxamide CAS NO 1628184-67-7 is a high-value, fluorinated cyclopropane derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclopropane ring and a trifluoromethyl group, is essential for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the metabolically stable trifluoromethyl group and the strained cyclopropane ring to enhance potency and bioavailability.
• Agrochemical Synthesis: Used in the design and synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorinated cyclopropane moiety can improve environmental stability and target specificity.
• Material Science Research: Employed in the development of specialty polymers and advanced materials, where its rigid structure can influence polymer backbone properties and performance.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on exploring the effects of fluorinated groups in molecular design.

Basic Information

Product Name	1-(Trifluoromethyl)Cyclopropane-1-Carboxamide
CAS No.	1628184-67-7
Molecular Formula	C5H6F3NO
Molecular Weight	153.10 g/mol
Synonyms	1-(Trifluoromethyl)cyclopropanecarboxamide; Cyclopropanecarboxamide, 1-(trifluoromethyl)-; 1-Trifluoromethylcyclopropane-1-carboxylic acid amide; α-(Trifluoromethyl)cyclopropanecarboxamide; (Trifluoromethyl)cyclopropanecarboxamide
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques like HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.