Description

2-(Cyclopropylmethoxy)-4-Fluorophenylboronic Acid is a specialized organoboron compound featuring a cyclopropylmethoxy and a fluorine substituent on the phenyl ring. This structural motif makes it a valuable high-purity building block for modern synthetic chemistry, particularly in cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific fluorinated aromatic components.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of fluorinated molecular probes and tags for imaging and diagnostic applications.
• Catalyst Ligand Synthesis: Useful for preparing sophisticated ligand frameworks in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	2-(Cyclopropylmethoxy)-4-Fluorophenylboronic Acid
CAS No.	1627839-42-2
Molecular Formula	C10H12BFO3
Molecular Weight	209.81 g/mol
Synonyms	[2-(Cyclopropylmethoxy)-4-fluorophenyl]boronic acid; 4-Fluoro-2-(cyclopropylmethoxy)benzeneboronic acid; 2-(Cyclopropylmethoxy)-4-fluorobenzeneboronic acid; (2-(Cyclopropylmethoxy)-4-fluorophenyl)boronic acid; Boronic acid, B-[2-(cyclopropylmethoxy)-4-fluorophenyl]-; CAS 1627839-42-2
EINECS	Contact for details

Quality Control

Our 2-(Cyclopropylmethoxy)-4-Fluorophenylboronic Acid is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.