Description

cis-4-Fluorooxolan-3-Amine is a high-purity, fluorinated heterocyclic amine building block of significant interest in advanced organic synthesis. Its unique stereochemistry and functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Building Block: Essential for introducing the fluorine atom into target molecules to modulate their bioavailability, metabolic stability, and binding affinity.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	cis-4-Fluorooxolan-3-Amine
CAS No.	1627196-90-0
Molecular Formula	C4H8FNO
Molecular Weight	105.11 g/mol
Synonyms	cis-3-Amino-4-fluorotetrahydrofuran; (3R,4S)-4-Fluorooxolan-3-amine (and its enantiomer); 4-Fluorooxolan-3-amine, cis-; 4-Fluoro-tetrahydrofuran-3-amine; 3-Amino-4-fluoro-tetrahydrofuran; Furan, 3-amino-4-fluoro-tetrahydro-, cis-; 1627196-90-0; 4-Fluorotetrahydrofuran-3-amine
EINECS	Contact for details

Quality Control

Every batch of cis-4-Fluorooxolan-3-Amine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure compliance with the highest purity standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.