Description

2’-Benzyl-2-Hydroxy-3-(Diphenylphosphino)-[1,1’-Binaphthalene] is a sophisticated chiral phosphine ligand, a key building block in asymmetric synthesis. Its value lies in enabling highly enantioselective catalytic transformations, which are critical for producing single-isomer pharmaceuticals and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric hydrogenation reactions.
• As a key component in catalysts for asymmetric C-C and C-X bond-forming reactions.
• For the synthesis of enantiomerically pure intermediates in active pharmaceutical ingredient (API) development.
• In academic and industrial research focused on novel catalytic methodologies.
• For the production of chiral agrochemicals and flavors/fragrances.
• As a specialty chemical for custom catalyst preparation and screening.

Basic Information

Item	Details
Product Name	2’-Benzyl-2-Hydroxy-3-(Diphenylphosphino)-[1,1’-Binaphthalene]
CAS No.	1621627-50-6
Molecular Formula	C39H29O1P1
Molecular Weight	544.62 g/mol
Synonyms	2'-Benzyl-2-hydroxy-3-(diphenylphosphino)-1,1'-binaphthyl; (R)- or (S)-2'-Benzyl-2-hydroxy-3-(diphenylphosphino)-[1,1'-binaphthalene]; Bn-HO-BINAP derivative; Chiral BINAP-type phosphine ligand; 2'-Benzyl-2'-hydroxy-3-(diphenylphosphino)-1,1'-binaphthyl; Contact for details on specific enantiomer.
EINECS	Contact for details

Quality Control

Our 2’-Benzyl-2-Hydroxy-3-(Diphenylphosphino)-[1,1’-Binaphthalene] is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, which is critical for catalytic performance. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, enantiomeric excess (if applicable), and key impurity profiles. Our quality systems support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.