Description

3,5-Difluoro-4-Methylphenylboronic Acid is a high-purity organoboron compound, a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require precise, reliable, and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides that benefit from the stability and bioactivity of difluoromethyl-substituted aromatic systems.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating fluorinated aromatic cores in electronic display and lighting materials, enhancing their performance and stability.
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific thermal, chemical, or surface properties.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new catalytic processes and material science applications.
• Ligand & Catalyst Preparation: Used to synthesize sophisticated ligands for transition metal catalysts used in asymmetric synthesis and other advanced reactions.

Basic Information

Product Name	3,5-Difluoro-4-Methylphenylboronic Acid
CAS No.	1621332-09-9
Molecular Formula	C7H7BF2O2
Molecular Weight	171.94 g/mol
Synonyms	(3,5-Difluoro-4-methylphenyl)boronic acid; 4-Methyl-3,5-difluorophenylboronic acid; B-(3,5-Difluoro-4-methylphenyl)boronic acid; 3,5-Difluoro-p-tolylboronic acid; 1621332-09-9; Boronic acid, B-(3,5-difluoro-4-methylphenyl)-; (4-Methyl-3,5-difluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.