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Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin, 2,6-Bis(3,5-Difluorophenyl)-4-Hydroxy-, 4-Oxide, (11Bs)- CAS NO 1620003-88-4
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CAS No.:1620003-88-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin, 2,6-Bis(3,5-Difluorophenyl)-4-Hydroxy-, 4-Oxide, (11Bs)- is a sophisticated, high-purity organophosphorus compound characterized by its unique fused ring structure and fluorinated aromatic substituents. This compound is of significant commercial interest as a specialized ligand or catalyst precursor in advanced synthetic chemistry, particularly for applications requiring precise stereochemical control. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active ingredients and complex molecular architectures.
Application
- Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective synthesis.
- Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
- Advanced Material Synthesis: Used in the preparation of specialized polymers or organic electronic materials where fluorinated components are required.
- Agrochemical Research: Potential application in the synthesis of novel, high-performance crop protection agents.
- Academic & Industrial R&D: A valuable reagent for methodological development in organic and organometallic chemistry.
Basic Information
| Product Name | Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin, 2,6-Bis(3,5-Difluorophenyl)-4-Hydroxy-, 4-Oxide, (11Bs)- |
| CAS No. | 1620003-88-4 |
| Molecular Formula | C32H16F4O4P |
| Molecular Weight | 580.44 g/mol |
| Synonyms | (11bS)-2,6-Bis(3,5-difluorophenyl)-4-hydroxy-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; (S)-2,6-Bis(3,5-difluorophenyl)-4-hydroxy-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; (S)-BINOL-Derived Phosphoric Acid with 3,5-Difluorophenyl Substituents; Chiral Phosphoric Acid Derivative; SPINOL-Based Phosphoric Acid Ligand; Asymmetric Organocatalyst Precursor |
| EINECS | Contact for details |
Quality Control
Every batch of this high-value compound is produced and analyzed under strict quality control protocols to ensure identity, purity, and chiral integrity. Our standard specification typically includes identification by spectroscopic methods (NMR, IR), chiral purity determination by HPLC, and quantitative assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your regulatory and R&D documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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