Description

Trifluoroacetic Acid CAS NO 1619991-24-0 is a highly versatile and potent fluorinated organic acid. It serves as a critical reagent and solvent in advanced organic synthesis and pharmaceutical manufacturing due to its strong acidity and excellent solvating properties. This product is essential for industries including pharmaceuticals, agrochemicals, and specialty chemical production, where it is used for peptide synthesis, deprotection reactions, and as a mobile phase modifier in analytical chromatography.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the introduction of the trifluoromethyl group and for deprotection in peptide and oligonucleotide synthesis.
• HPLC Analysis: Used as a volatile ion-pairing agent and mobile phase modifier in reverse-phase chromatography for separating polar compounds and biomolecules.
• Organic Solvent & Catalyst: Acts as a powerful solvent for resins and polymers and as an acid catalyst in various organic transformations, including esterifications and rearrangements.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides and pesticides that incorporate fluorine for enhanced efficacy and environmental profile.
• Polymer Industry: Utilized in the production and modification of specialty fluoropolymers.
• Laboratory Research: A standard reagent in research laboratories for method development and small-scale synthesis.

Basic Information

Product Name	Trifluoroacetic Acid
CAS No.	1619991-24-0
Molecular Formula	C2HF3O2
Molecular Weight	114.02 g/mol
Synonyms	Trifluoroethanoic Acid; TFA; Perfluoroacetic Acid; 2,2,2-Trifluoroacetic Acid; Acetic Acid, Trifluoro-; CF3COOH; Kyselina trifluoroctova; Trifluoressigsaeure
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for demanding synthetic and analytical applications. Certificates of Analysis (COA) documenting purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile and strong acid/organic solvent nature, containers must be kept tightly sealed to prevent moisture absorption and release of vapors.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Assay (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Residue on Evaporation	≤ 0.005%
Chloride (Cl)	≤ 10 ppm
Sulfate (SO4)	≤ 10 ppm
Heavy Metals (as Pb)	≤ 5 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.