Description

tert-Butyl 4-Cyano-2,6-Dimethylbenzylcarbamate (Wx191479) is a high-purity, advanced pharmaceutical intermediate featuring a carbamate-protected benzylamine core with cyano and dimethyl substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, process development chemists, and large-scale API manufacturers seeking a reliable and high-quality building block for their synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates, especially those with complex aromatic amine structures.
• Medicinal Chemistry Research: Used in the discovery and optimization phase for creating libraries of compounds targeting specific biological pathways.
• Process Development & Scale-up: Serves as a critical starting material or intermediate for developing robust, kilogram-to-ton scale manufacturing processes for APIs.
• CNS Drug Synthesis: Particularly valuable in constructing molecules designed to cross the blood-brain barrier for treating neurological conditions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and catalysis.

Basic Information

Product Name	tert-Butyl 4-Cyano-2,6-Dimethylbenzylcarbamate (Wx191479)
CAS No.	1618647-92-9
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	Boc-4-Cyano-2,6-dimethylbenzylamine; tert-Butyl N-[(4-Cyano-2,6-dimethylphenyl)methyl]carbamate; 1,3-Dimethyl-4-(aminomethyl)-2-cyanobenzene tert-Butylcarbamate; 4-Cyano-2,6-dimethylbenzylcarbamic acid tert-butyl ester; Wx191479; (4-Cyano-2,6-dimethylbenzyl)carbamic acid tert-butyl ester; N-Boc-4-cyano-2,6-dimethylbenzylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyano-2,6-Dimethylbenzylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.