Description

4-Amino-2-Chloro-5-Methoxybenzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring distinct amino, chloro, and methoxy substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its substituted benzene core contributes to biological activity.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and high-performance pigments, leveraging its amino and nitrile functional groups.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its electron-withdrawing nitrile group and potential for further functionalization.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Buchwald-Hartwig amination or Suzuki coupling, facilitating the creation of diverse biaryl structures.

Basic Information

Product Name	4-Amino-2-Chloro-5-Methoxybenzonitrile
CAS No.	1613730-68-9
Molecular Formula	C8H7ClN2O
Molecular Weight	182.61 g/mol
Synonyms	2-Chloro-4-cyano-5-methoxyaniline; 5-Methoxy-2-chloro-4-cyanoaniline; 4-Cyano-2-chloro-5-methoxyaniline; Benzonitrile, 4-amino-2-chloro-5-methoxy-; 2-Chloro-5-methoxy-4-aminobenzonitrile; 4-Amino-2-chloro-5-methoxybenzenecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-2-Chloro-5-Methoxybenzonitrile is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the demanding requirements of research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.