Description

(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole is a high-purity, chiral organophosphorus compound with a unique binaphthol-derived backbone, serving as a sophisticated ligand or catalyst precursor in advanced synthetic chemistry. Its value lies in enabling highly selective and efficient asymmetric transformations, critical for producing enantiomerically pure intermediates in pharmaceutical and fine chemical manufacturing. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control for complex molecule synthesis. CAS No. 1610785-35-7.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, including hydrogenation, cross-coupling, and C-H activation.
• As a key precursor for synthesizing novel organocatalysts with tailored steric and electronic properties.
• In the research and development of new active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• For the asymmetric synthesis of complex natural products and bioactive molecules in academic and industrial laboratories.
• As a specialty additive or co-catalyst in polymerization processes to control polymer tacticity.
• In method development and scale-up studies for catalytic processes in fine chemical production.

Basic Information

Item	Details
Product Name	(2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole
CAS No.	1610785-35-7
Molecular Formula	C28H34O2P2
Molecular Weight	464.51 g/mol
Synonyms	3,3'-Di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bi-1,3-benzoxaphosphole; (R,R)-3,3'-Di-tert-butyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d][1,3]oxaphosphole; BIBOP Derivative; Chiral Binaphthol Phosphite; DTBP-BIBOP; (R)-DTB-BIBOP Ligand; P-Chiral Biphenol Derivative; Asymmetric Phosphorus Ligand
EINECS	Contact for details

Quality Control

Every batch of our (2R,2'R,3R,3'R)-3,3'-Di-tert-Butyl-2,2',3,3'-Tetrahydro-2,2'-Bibenzo[D][1,3]Oxaphosphole is manufactured and tested under strict quality management systems to ensure exceptional purity and chiral integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity, and identity confirmation. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container must be kept sealed under inert gas after each use to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.