Description

n-Ethyl Tadalafil is a high-purity pharmaceutical intermediate and research chemical, structurally related to Tadalafil. This compound is critical for the development and synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical R&D laboratories, API manufacturers, and fine chemical synthesis specialists engaged in advanced medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel PDE5 inhibitor analogs and related therapeutic compounds.
• Research & Development: Used in academic and industrial research for structure-activity relationship (SAR) studies and biological screening.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	n-Ethyl Tadalafil
CAS No.	1609405-34-6
Molecular Formula	C24H27N3O4
Molecular Weight	421.49 g/mol
Synonyms	N-Ethyl Tadalafil; Ethyl Tadalafil; (6R,12aR)-2-Ethyl-1,2,3,4,6,7,12,12a-octahydro-6-(1,3-benzodioxol-5-yl)pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Tadalafil N-Ethyl Analog; PDE5 Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our n-Ethyl Tadalafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.