Description

Bms-986165 Related Compound 6 is a high-purity chemical reference standard and synthetic intermediate of significant importance in pharmaceutical research and development. Its primary value lies in serving as a critical impurity marker and process-related compound for the development and quality control of BMS-986165, a key investigational therapeutic agent. This compound is essential for researchers and quality assurance professionals in the pharmaceutical and biotechnology sectors who require reliable reference materials for method validation, stability studies, and regulatory filings.

Application

• Pharmaceutical Reference Standard: Used as a certified impurity standard for the analytical method development and validation of BMS-986165 active pharmaceutical ingredient (API).
• Process Chemistry Research: Serves as a key intermediate or related substance in the synthetic pathway optimization for TYK2 inhibitor compounds.
• Quality Control & Assurance: Critical for HPLC, LC-MS, and other chromatographic assays to quantify and control impurities in drug substance batches, ensuring compliance with ICH guidelines.
• Regulatory Compliance: Supports the preparation of regulatory submission documents (e.g., for FDA, EMA) by providing characterized material for impurity profiles.
• Stability Studies: Employed in forced degradation and long-term stability testing to identify and track degradation products.
• Academic & Contract Research: Utilized in biochemical and pharmacological research to study structure-activity relationships (SAR) within the TYK2 inhibitor class.

Basic Information

Product Name	Bms-986165 Related Compound 6
CAS No.	1609394-23-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BMS-986165 Impurity; BMS-986165 Related Substance 6; BMS-986165 Process Impurity; TYK2 Inhibitor Related Compound 6; (S)-2-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-3-cyclopropyl-1-(1-methyl-1H-pyrazol-4-yl)propan-1-one (proposed); Deucravacitinib Related Compound 6; 1609394-23-1; BMS 986165 RC6
EINECS	Contact for details

Quality Control

Every batch of Bms-986165 Related Compound 6 is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity confirmation, purity analysis, and impurity profiling using advanced techniques like HPLC, LC-MS, and NMR to ensure they meet the exacting standards required for pharmaceutical reference materials. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting compliance with cGMP and ICH Q3A/B guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time matches reference standard
Identification (MS)	Mass spectrum conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity ≤ 1.0% Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.