Description

1-Cyclobutyl-3-Ethynylbenzene is a specialized aromatic compound featuring both a cyclobutyl and an ethynyl functional group. This unique structure makes it a valuable advanced intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, materials science, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those requiring rigid, three-dimensional scaffolds.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the cyclobutyl moiety can influence biological activity and environmental stability.
• Material Science: Serves as a monomer or precursor in the development of advanced polymers and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Sonogashira, Heck) to construct complex aromatic systems for various research applications.
• Ligand & Catalyst Development: Useful for creating novel ligands for catalysis in asymmetric synthesis and other transition metal-catalyzed processes.

Basic Information

Product Name	1-Cyclobutyl-3-Ethynylbenzene
CAS No.	1602816-47-6
Molecular Formula	C₁₂H₁₂
Molecular Weight	156.22 g/mol
Synonyms	3-Ethynyl-1-cyclobutylbenzene; m-Ethynylcyclobutylbenzene; 1-Cyclobutyl-3-ethynyl-benzene; Benzene, 1-cyclobutyl-3-ethynyl-; (3-Cyclobutylphenyl)acetylene
EINECS	Contact for details

Quality Control

Our 1-Cyclobutyl-3-Ethynylbenzene is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.