Description

2-(2-Fluoro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality reagents for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis projects.

Basic Information

Product Name	2-(2-Fluoro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1599432-41-3
Molecular Formula	C₁₃H₁₈BFO₃
Molecular Weight	252.09 g/mol
Synonyms	2-Fluoro-6-methoxyphenylboronic acid pinacol ester; (2-Fluoro-6-methoxyphenyl)boronic acid pinacol ester; 2-(2-Fluoro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-fluoro-6-methoxyphenyl)boronate; (2-Fluoro-6-methoxyphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 2-Fluoro-6-methoxybenzeneboronic acid pinacol ester; 1599432-41-3; B-(2-Fluoro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.