Description

2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected boronic acid building block, enabling complex cross-coupling reactions with exceptional selectivity and stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing novel fluorinated aromatic scaffolds. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the development of advanced active ingredients where the fluorinated phenyl ring confers desirable biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Employed as a building block for creating fluorinated aromatic cores in electronic and display materials to fine-tune electronic properties.
• Polymer Chemistry: Facilitates the incorporation of functionalized aromatic units into specialty polymers via catalytic coupling methodologies.
• Chemical Biology & Probe Development: Useful for tagging and modifying biomolecules or creating fluorescent probes due to its reactive boronate functionality.
• Process Chemistry & Scale-up: The pinacol ester protection offers enhanced stability for handling and storage during large-scale manufacturing processes.

Basic Information

Item	Details
Product Name	2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester
CAS No.	1599432-40-2
Molecular Formula	C14H20BFO4
Molecular Weight	282.12 g/mol
Synonyms	2-Fluoro-6-(Methoxymethoxy)Benzeneboronic Acid Pinacol Ester; (2-Fluoro-6-(methoxymethoxy)phenyl)boronic Acid Pinacol Ester; 2-Fluoro-6-MOM-Phenylboronic Acid Pinacol Ester; 2-Fluoro-6-(Methoxymethoxy)phenyl-1,3,2-dioxaborinane, 2,4,4,5,5-Pentamethyl-; B-[2-Fluoro-6-(methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol 2-Fluoro-6-(methoxymethoxy)phenylboronate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Methoxymethoxy)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and GC-MS, to ensure identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all test results are provided and available upon request. We adhere to cGMP guidelines for production where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (argon or nitrogen) in a desiccator. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.