Description

S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide is a high-purity, chiral sulfinamide-phosphine hybrid ligand, a critical building block in modern asymmetric synthesis. Its value lies in its ability to act as a highly effective chiral auxiliary and ligand, enabling the precise control of stereochemistry in the formation of new carbon-carbon and carbon-heteroatom bonds. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• As a chiral ligand in asymmetric transition metal catalysis, such as rhodium- or iridium-catalyzed hydrogenations.
• As a chiral auxiliary in the stereoselective synthesis of amines, amino acids, and other nitrogen-containing compounds.
• Key intermediate in the research and development of novel pharmaceutical candidates requiring high enantiomeric purity.
• Used in the synthesis of complex natural products and specialty chemicals where precise stereocontrol is paramount.
• Facilitates the preparation of other custom chiral phosphine ligands and organocatalysts.
• Applicable in academic and industrial R&D for methodological studies in asymmetric synthesis.

Basic Information

Product Name	S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1595319-98-4
Molecular Formula	C24H28NOPS
Molecular Weight	409.52 g/mol
Synonyms	(S)-N-[(1S)-1-[2-(Diphenylphosphino)phenyl]ethyl]-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide, N-[(1S)-1-[2-(diphenylphosphino)phenyl]ethyl]-; (S)-N-((S)-1-(2-(Diphenylphosphino)phenyl)ethyl)-2-methylpropane-2-sulfinamide; Chiral Sulfinamide-Phosphine Ligand; (S,S)-PS-Sulfinamide Ligand; tert-Butylsulfinyl Phosphine Ligand; (S)-N-[(S)-1-(2-(Diphenylphosphanyl)phenyl)ethyl]-2-methylpropane-2-sulfinamide
EINECS	Contact for details

Quality Control

Our production of S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]Ethyl]-2-Methyl-2-Propanesulfinamide adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity, critical for sensitive asymmetric synthesis. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.