Description

[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl](4-Methoxyphenyl)Methyl]-2-Methyl-2-Propanesulfinamide is a high-purity, chiral sulfinamide-phosphine hybrid ligand, a critical component in asymmetric synthesis. Its value lies in enabling highly enantioselective transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. This advanced chiral auxiliary is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, cross-coupling, and hydroformylation.
• Critical for the stereoselective synthesis of active pharmaceutical ingredients (APIs) and key drug intermediates.
• Used in the development of agrochemicals and other bioactive compounds requiring specific enantiomeric purity.
• Facilitates academic and industrial research in novel catalytic methodologies and reaction optimization.
• Employed in the fine chemical industry for the production of high-value, enantiomerically pure compounds.
• Serves as a building block or precursor for more complex, tailor-made chiral catalysts and auxiliaries.

Basic Information

Product Name	[S(R)]-n-[(R)-[2-(Diphenylphosphino)Phenyl](4-Methoxyphenyl)Methyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1595319-96-2
Molecular Formula	C30H32NO2PS
Molecular Weight	501.62 g/mol
Synonyms	(S)-N-[(R)-(2-(Diphenylphosphino)phenyl)(4-methoxyphenyl)methyl]-2-methylpropane-2-sulfinamide; (S)-N-((R)-(2-(Diphenylphosphino)phenyl)(4-methoxyphenyl)methyl)-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide, N-[(R)-[2-(diphenylphosphino)phenyl](4-methoxyphenyl)methyl]-; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Synthesis Ligand; Hybrid P,N-Ligand; Sulfinyl Imine Phosphine Ligand
EINECS	Contact for details

Quality Control

Our production of this advanced chiral ligand adheres to stringent quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment to support your critical R&D and cGMP manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere. This compound is moisture-sensitive and should be handled in a dry environment to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.