Description

[S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is a high-purity, chiral sulfinamide-phosphine hybrid ligand, a critical building block in asymmetric synthesis. Its value lies in its ability to act as a highly effective chiral auxiliary or ligand, enabling the production of enantiomerically pure compounds with high stereoselectivity. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical and fine chemical industries developing novel active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and hydroformylation.
• As a chiral auxiliary in the stereoselective synthesis of complex organic molecules and natural products.
• In the research and development of novel pharmaceutical compounds requiring high enantiomeric purity.
• For the synthesis of advanced intermediates in agrochemical and material science applications.
• In academic and industrial research focused on developing new catalytic methodologies.
• For process development and scale-up of chiral drug candidates in pharmaceutical manufacturing.

Basic Information

Product Name	[S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide
CAS No.	1595319-94-0
Molecular Formula	C29H36NOPS
Molecular Weight	477.63 g/mol
Synonyms	(S)-tert-Butanesulfinamide, (R)-[1-[2-(Diphenylphosphino)phenyl]-2,2-dimethylpropyl]-; (S)-N-[(1R)-1-[2-(Diphenylphosphino)phenyl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; (S)-N-[(R)-1-[2-(Diphenylphosphino)phenyl]-2,2-dimethylpropyl]-2-methylpropane-2-sulfinamide; tert-Butanesulfinamide, N-[(1R)-1-[2-(diphenylphosphino)phenyl]-2,2-dimethylpropyl]-, (S)-; Chiral Sulfinamide-Phosphine Ligand; Asymmetric Synthesis Ligand; Sulfinyl Phosphine Ligand
EINECS	Contact for details

Quality Control

Our [S(R)]-n-[(1S)-1-[2-(Diphenylphosphino)Phenyl]-2,2-Dimethylpropyl]-2-Methyl-2-Propanesulfinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and purity assessment to meet exacting research and development standards. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.