Description

2-Bromo-6-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex biaryl and heterobiaryl scaffolds. The pinacol ester group enhances stability and handling, making it a reliable reagent for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated and brominated biphenyl motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where specific halogenated aromatic structures are required for bioactivity.
• Material Science: Serves as a monomer or precursor in the creation of advanced organic electronic materials, such as OLEDs and semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized for constructing molecular probes and tags used in biochemical assay development and diagnostic applications.
• Academic & Contract Research: A vital reagent for methodological development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Bromo-6-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1595078-06-0
Molecular Formula	C12H15BBrFO2
Molecular Weight	301.96 g/mol
Synonyms	2-Bromo-6-fluorobenzeneboronic acid pinacol ester; (2-Bromo-6-fluorophenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(2-bromo-6-fluorophenyl)-1,3,2-dioxaborolane; 2-(2-Bromo-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Boronic acid, B-(2-bromo-6-fluorophenyl)-, 1,1-dimethylethyl ester; 2-Bromo-6-fluorophenylboronic acid neopentyl glycol ester (common alternative); 2-Bromo-6-fluoro phenyl BPin
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.