Description

2-(2-Bromo-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and bromo-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the unique properties of the trifluoromethyl group enhance biological activity.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronate ester coupling partner with aryl/vinyl halides to form biaryl and other conjugated structures.
• Ligand and Catalyst Development: Employed in the research and production of specialized ligands and organometallic catalysts.
• Material Science Research: A building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Synthesis: Utilized in the creation of molecular probes and labeled compounds for diagnostic and research applications.

Basic Information

Product Name	2-(2-Bromo-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1595078-04-8
Molecular Formula	C13H15BBrF3O2
Molecular Weight	349.97 g/mol
Synonyms	2-Bromo-4-(trifluoromethyl)phenylboronic acid pinacol ester; (2-Bromo-4-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-Bromo-4-trifluoromethylbenzeneboronic acid pinacol ester; Pinacol (2-Bromo-4-(trifluoromethyl)phenyl)boronate; 2-(2-Bromo-4-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1595078-04-8; B-(2-Bromo-4-(trifluoromethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-4-(Trifluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry inert atmosphere due to the moisture-sensitive nature of boronic esters.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.