Description

2-Bromo-4-Fluorophenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific halogenated aromatic motifs are required for bioactivity.
• Material Science Research: Serves as a precursor for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, through controlled polymerization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes and tags for studying biological systems and protein interactions.

Basic Information

Product Name	2-Bromo-4-Fluorophenylboronic Acid Pinacol Ester
CAS No.	1595078-01-5
Molecular Formula	C₁₂H₁₅BBrFO₂
Molecular Weight	301.96 g/mol
Synonyms	2-Bromo-4-fluorophenylboronic acid pinacol ester; (2-Bromo-4-fluorophenyl)boronic acid pinacol ester; 4-Fluoro-2-bromophenylboronic acid pinacol ester; 2-Bromo-4-fluorobenzeneboronic acid pinacol ester; Pinacol (2-bromo-4-fluorophenyl)boronate; 2-Bromo-4-fluorophenyl-Bpin; B-(2-Bromo-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Every batch of our 2-Bromo-4-Fluorophenylboronic Acid Pinacol Ester is produced under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical characterization including NMR, HPLC, and GC. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.