Description

(5-Cyclopropyl-2-Fluorophenyl)Boronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the discovery and scale-up of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated and cyclopropyl-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized for labeling and modifying biomolecules or creating chemical probes for biological target identification and validation.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CDMOs serving the global life sciences market.

Basic Information

Product Name	(5-Cyclopropyl-2-Fluorophenyl)Boronic Acid
CAS No.	1586045-56-8
Molecular Formula	C9H10BFO2
Molecular Weight	179.99 g/mol
Synonyms	(5-Cyclopropyl-2-fluorophenyl)boronic acid; 2-Fluoro-5-cyclopropylbenzeneboronic acid; Boronic acid, B-(5-cyclopropyl-2-fluorophenyl)-; 5-Cyclopropyl-2-fluorobenzeneboronic acid; (2-Fluoro-5-cyclopropylphenyl)boronic acid; CAS 1586045-56-8
EINECS	Contact for details

Quality Control

Our (5-Cyclopropyl-2-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.