Description

2-(2,4-Difluorophenyl)-2,2-Difluoroethan-1-Ol is a high-purity fluorinated alcohol intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is key to modulating biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in antiviral, antifungal, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), contributing to improved stability and performance.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing material properties like chemical resistance and surface energy.
• Organic Synthesis Building Block: A versatile reagent for constructing complex organic frameworks in academic and industrial research laboratories.
• Fluorinated Surfactant Precursor: Used in the development of specialty surfactants and surface coatings with unique wetting and leveling characteristics.

Basic Information

Product Name	2-(2,4-Difluorophenyl)-2,2-Difluoroethan-1-Ol
CAS No.	1581274-08-9
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	2,2-Difluoro-2-(2,4-difluorophenyl)ethanol; 1-(2,4-Difluorophenyl)-2,2-difluoroethan-1-ol; 2,2-Difluoro-1-(2,4-difluorophenyl)ethanol; α,α-Difluoro-2,4-difluorobenzeneethanol; 2-(2,4-Difluorophenyl)-2,2-difluoroethanol; DFDFE; (2,4-Difluorophenyl)difluoroethanol
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluorophenyl)-2,2-Difluoroethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.