Description

(R)-4-Oxide-2,6-Bis[4-(1,1-Dimethylethyl)Phenyl]-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxydinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin is a high-purity, chiral organophosphorus compound characterized by its complex, sterically hindered dinaphtho-dioxaphosphepin core structure. This compound matters as a sophisticated ligand precursor or catalyst in asymmetric synthesis, enabling the production of enantiomerically pure intermediates critical for advanced pharmaceuticals and specialty chemicals. It is primarily needed by research institutions and fine chemical manufacturers engaged in developing novel catalytic systems and high-value chiral molecules.

Application

• Asymmetric Catalysis: Serving as a precursor for chiral phosphine-phosphite or related ligands in transition metal catalysis for enantioselective hydrogenation, hydroformylation, and C-C bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enabling the production of single-enantiomer active pharmaceutical ingredients (APIs) for therapeutic agents targeting central nervous system, cardiovascular, and oncological diseases.
• Advanced Material Research: Utilized in the development of chiral polymers or frameworks with potential applications in sensors, chromatography, and nonlinear optics.
• Agrochemical Development: Acting as a key chiral building block for the synthesis of novel, enantiomerically pure pesticides and herbicides.
• Academic & Industrial R&D: A valuable tool compound for studying structure-activity relationships in catalysis and exploring new reaction methodologies in organic chemistry.

Basic Information

Product Name	(R)-4-Oxide-2,6-Bis[4-(1,1-Dimethylethyl)Phenyl]-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxydinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin
CAS No.	1569807-27-7
Molecular Formula	C44H49O4P
Molecular Weight	672.83 g/mol
Synonyms	(R)-4-Hydroxy-4-oxido-2,6-bis(4-tert-butylphenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; (R)-H8-BINOL-Derived Phosphine-Phosphite Monoxide Ligand Precursor; (R)-4-Hydroxy-2,6-bis(4-tert-butylphenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; (R)-Octahydro-DINAP(O)(OH) Derivative; Chiral Dioxaphosphepin P-Oxide; CAS 1569807-27-7
EINECS	Contact for details

Quality Control

Every batch of our (R)-4-Oxide-2,6-Bis[4-(1,1-Dimethyl)Phenyl]-Octahydro-4-Hydroxydinaphtho-Dioxaphosphepin is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to guarantee chemical identity, high enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.