Description

(11Br)-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxy-2,6-Bis([1,1':3',1''-Terphenyl]-5'-Yl)-4-Oxide-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin, 99% E.E. is a high-purity, chiral organophosphorus compound with a complex, sterically demanding structure. This compound is significant as a highly enantioselective ligand or catalyst precursor in advanced synthetic chemistry, enabling the production of optically active molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for asymmetric synthesis and process development.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions (e.g., hydrogenation, cross-coupling).
• As a catalyst precursor for the synthesis of enantiomerically pure pharmaceutical intermediates.
• In methodology development for creating novel asymmetric synthetic pathways in academic and industrial R&D.
• For the production of agrochemicals requiring specific stereochemistry for enhanced activity and safety.
• As a key building block or reagent in the synthesis of complex natural products and specialty chemicals.
• In process chemistry optimization for scaling up the manufacture of chiral active pharmaceutical ingredients (APIs).

Basic Information

Product Name	(11Br)-8,9,10,11,12,13,14,15-Octahydro-4-Hydroxy-2,6-Bis([1,1':3',1''-Terphenyl]-5'-Yl)-4-Oxide-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin, 99% E.E.
CAS No.	1569807-15-3
Molecular Formula	C70H48BrO4P
Molecular Weight	1039.90 g/mol
Synonyms	(11Br)-H8-BINOL-DTBP; DTBP-BINOL Phosphoric Acid Bromide Derivative; Chiral Br-DTBP-BINOL Phosphoric Acid; Brominated DTBP-BINOL-Based Phosphoric Acid Catalyst; (R)- or (S)-2,6-Bis(3,5-di-tert-butylphenyl)-4-(bromo)-4-hydroxy-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-Oxide; Enantiomerically Enriched BINOL-DTBP Phosphoric Acid Bromide; Asymmetric Organocatalyst Ligand; 1569807-15-3.
EINECS	Contact for details

Quality Control

Our 99% enantiomeric excess (E.E.) grade is produced under controlled conditions to ensure batch-to-batch consistency and high optical purity. Every lot undergoes rigorous analytical testing, including HPLC for enantiopurity and NMR for structural confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container should be stored in a cool, dry place, ideally under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature is 2-8°C to maintain stability and enantiomeric purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (E.E.)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.