Description

3-(Benzyloxy)Cyclobutanecarbonitrile is a versatile and high-value chemical intermediate featuring a cyclobutane ring functionalized with a benzyloxy group and a nitrile moiety. This unique structure makes it a critical building block for the synthesis of complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for creating monomers or additives aimed at developing polymers with specific optical or mechanical properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic chemistry, including ring-opening and functional group transformation reactions.
• Custom Synthesis & Scale-Up: Foundation for custom manufacturing projects, supporting process optimization from milligram to kilogram scale for client-specific molecules.

Basic Information

Product Name	3-(Benzyloxy)Cyclobutanecarbonitrile
CAS No.	1566444-05-0
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	Cyclobutanecarbonitrile, 3-(phenylmethoxy)-; 3-(Benzyloxy)cyclobutanecarbonitrile; 3-Benzyloxycyclobutanecarbonitrile; 3-(Phenylmethoxy)cyclobutanecarbonitrile; 1566444-05-0; 3-Benzyloxy-cyclobutanecarbonitrile; 3-(Benzyloxy)cyclobutanenitrile
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.