Description

(2S,3S,4Ar,8Ar)-2,3-Bis[2-(Diphenylphosphino)Phenyl]-1,4-Dimethyldecahydroquinoxaline is a sophisticated, chiral bisphosphine ligand designed for high-performance asymmetric catalysis. Its value lies in providing exceptional stereocontrol and activity in transition metal-catalyzed reactions, enabling the efficient synthesis of enantiomerically pure compounds. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and highly selective catalysts for complex synthetic transformations.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, critical for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Asymmetric C-C Bond Formation: Facilitates cross-coupling, allylic alkylation, and other C-C bond-forming reactions with high enantiomeric excess.
• Pharmaceutical Intermediate Synthesis: Enables the production of chiral building blocks for drug discovery and development programs.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Catalyst Development & Screening: Serves as a valuable tool for R&D in developing new catalytic systems and optimizing reaction conditions.

Basic Information

Item	Details
Product Name	(2S,3S,4Ar,8Ar)-2,3-Bis[2-(Diphenylphosphino)Phenyl]-1,4-Dimethyldecahydroquinoxaline
CAS No.	1562581-18-3
Molecular Formula	C46H46N2P2
Molecular Weight	688.82 g/mol
Synonyms	Me-DuPhos Quinoxaline Derivative; (S,S)-Me-DuPhos Quinoxaline; Chiral Quinoxaline-Based Bisphosphine Ligand; DuPhos-Type Ligand; (2S,3S)-2,3-Bis(2-diphenylphosphinophenyl)-1,4-dimethyl-decahydroquinoxaline; (S,S)-2,3-Bis(2-diphenylphosphinophenyl)-1,4-dimethyl-decahydroquinoxaline; Asymmetric Hydrogenation Ligand; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of our (2S,3S,4Ar,8Ar)-2,3-Bis[2-(Diphenylphosphino)Phenyl]-1,4-Dimethyldecahydroquinoxaline is manufactured and tested under strict quality management systems. We ensure high chemical and chiral purity through advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific parameters is provided with each shipment to guarantee consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.