Description

4-Benzyloxy-2-(Trifluoromethoxy)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise, functionalized intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring the trifluoromethoxy and benzyloxy pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science: Building block for creating advanced organic electronic materials, liquid crystals, and polymers via palladium-catalyzed coupling reactions.
• Chemical Research: Versatile reagent in academic and industrial R&D labs for constructing complex biaryl and heterobiaryl structures.
• Ligand and Catalyst Development: Intermediate for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Benzyloxy-2-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	1562343-86-5
Molecular Formula	C14H12BF3O4
Molecular Weight	312.05 g/mol
Synonyms	[4-(Benzyloxy)-2-(trifluoromethoxy)phenyl]boronic acid; 2-(Trifluoromethoxy)-4-(phenylmethoxy)benzeneboronic acid; 4-(Benzyloxy)-2-(trifluoromethoxy)benzeneboronic acid; B-[4-(Benzyloxy)-2-(trifluoromethoxy)phenyl]boronic acid; 4-Benzyloxy-2-trifluoromethoxyphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full batch traceability are provided to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.