Description

2-Cyclopropyl-2,2-difluoroacetic acid is a high-purity fluorinated organic acid building block of significant interest in advanced chemical synthesis. Its unique structure, featuring a cyclopropyl ring and a difluoroacetic acid moiety, makes it a valuable precursor for creating novel compounds with tailored properties. This material is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries. It serves as a critical intermediate for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the cyclopropyl and fluorine groups can enhance biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and liquid crystals that require specific fluorinated components.
• Organic Synthesis Reagent: Employed as a versatile reagent in academic and industrial R&D for introducing the cyclopropyl-difluoroacetyl group into complex molecular architectures.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and reaction pathways in organofluorine chemistry.

Basic Information

Product Name	2-Cyclopropyl-2,2-difluoroacetic Acid
CAS No.	1557661-16-1
Molecular Formula	C5H6F2O2
Molecular Weight	136.10 g/mol
Synonyms	2,2-Difluoro-2-cyclopropylacetic Acid; Cyclopropanedifluoroacetic Acid; α,α-Difluorocyclopropaneacetic Acid; 2-Cyclopropyl-2,2-difluoroethanoic Acid; (Cyclopropyl)difluoroacetic Acid; Difluoro(cyclopropyl)acetic Acid; 1557661-16-1
EINECS	Contact for details

Quality Control

Our production of 2-Cyclopropyl-2,2-difluoroacetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support customer audits and can tailor specifications to meet specific project requirements, including those for cGMP or research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.