Description

1-Fluorocyclopentanecarboxylic Acid is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorine atom on a cyclopentane ring, makes it a critical intermediate for introducing conformational and electronic modifications into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Fluorine Chemistry Research: A valuable substrate for studying novel fluorination reactions and the stereoelectronic effects of fluorine in alicyclic systems.
• Ligand and Catalyst Development: Employed to construct fluorinated ligands for metal complexes used in asymmetric catalysis and other synthetic transformations.
• Diagnostic Agent Synthesis: Potential use as a building block for Positron Emission Tomography (PET) tracer molecules containing the fluorine-18 isotope.

Basic Information

Product Name	1-Fluorocyclopentanecarboxylic Acid
CAS No.	1557370-29-2
Molecular Formula	C6H9FO2
Molecular Weight	132.13 g/mol
Synonyms	1-Fluorocyclopentane-1-carboxylic Acid; Cyclopentanecarboxylic acid, 1-fluoro-; Fluorocyclopentanecarboxylic Acid; 1-Fluoro-1-cyclopentanecarboxylic Acid; 1-Fluorocyclopentylcarboxylic Acid; 1-Fluorocyclopentane carboxylic acid; 1-Fluorocyclopentane-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Fluorocyclopentanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.