Description

Benzeneacetic Acid, 2-Chloro-α,α,4-Trifluoro- is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its unique trifluoromethyl and chloro substitution pattern, which imparts desirable electronic and steric properties to target molecules. It is primarily utilized by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Advanced Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Chemical Research & Development: A versatile building block for exploring novel reaction pathways and creating compound libraries in academic and industrial R&D settings.

Basic Information

Product Name	Benzeneacetic Acid, 2-Chloro-α,α,4-Trifluoro-
CAS No.	1551074-08-8
Molecular Formula	C8H4ClF3O2
Molecular Weight	224.56 g/mol
Synonyms	2-Chloro-α,α,4-trifluorobenzeneacetic Acid; 2-Chloro-α,α,4-trifluorophenylacetic Acid; (2-Chloro-α,α,4-trifluorophenyl)acetic Acid; α,α,4-Trifluoro-2-chlorobenzeneacetic Acid; 2-Chloro-4-(trifluoromethyl)phenylacetic Acid (common misnomer); 2-Chloro-α,α,4-trifluoro-benzeneacetic acid; 1551074-08-8 (CAS Index Name); 2-Chloro-α,α,4-trifluoro-benzenacetic acid
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 2-Chloro-α,α,4-Trifluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.