Description

2-Amino-6-Bromo-3-Fluorobenzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique molecular architecture, featuring amino, bromo, and fluoro substituents on a benzonitrile core, which makes it an essential intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing advanced dyes and functional pigments.

Basic Information

Product Name	2-Amino-6-Bromo-3-Fluorobenzonitrile
CAS No.	1550664-84-0
Molecular Formula	C7H4BrFN2
Molecular Weight	215.03 g/mol
Synonyms	6-Bromo-3-fluoro-2-aminobenzonitrile; 2-Amino-6-bromo-3-fluorobenzonitrile; 3-Fluoro-2-amino-6-bromobenzonitrile; Benzonitrile, 2-amino-6-bromo-3-fluoro-; 1550664-84-0; 6-Bromo-3-fluoroanthranilonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Bromo-3-Fluorobenzonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.