Description

Ticagrelor Related Compound 70 Hcl is a high-purity chemical reference standard, specifically identified as a related substance of the antiplatelet drug Ticagrelor. This compound is critical for pharmaceutical research and development, serving as a key marker for impurity profiling, method validation, and ensuring drug safety and efficacy. It is primarily utilized by analytical chemists, quality control laboratories, and R&D departments within the global pharmaceutical and biotechnology industries to maintain stringent regulatory compliance.

Application

• Pharmaceutical Impurity Reference Standard: Used as a certified reference material for the identification and quantification of specific impurities in Ticagrelor active pharmaceutical ingredient (API) and finished dosage forms.
• Analytical Method Development & Validation: Essential for developing, optimizing, and validating HPLC, UPLC, or LC-MS methods to ensure accurate impurity detection limits.
• Quality Control & Assurance (QC/QA): Provides a benchmark for routine batch testing in pharmaceutical manufacturing to comply with ICH Q3A/B guidelines on impurities.
• Stability Studies: Employed to monitor the formation of degradation products in Ticagrelor formulations under various stress conditions.
• Regulatory Submissions: Supports regulatory filings (e.g., for FDA, EMA) by providing necessary data on impurity characterization and control strategies.
• Research on Drug Metabolism & Degradation Pathways: Aids in studying the chemical behavior and stability profile of Ticagrelor.

Basic Information

Product Name	Ticagrelor Related Compound 70 Hcl
CAS No.	1549834-66-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ticagrelor Impurity 70 Hcl; Ticagrelor Related Substance 70 Hcl; Ticagrelor EP Impurity 70 Hcl; Ticagrelor USP Related Compound 70 Hcl; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol hydrochloride; AZD6140 Related Compound 70 Hcl; Brilinta Related Compound 70 Hcl
EINECS	Contact for details

Quality Control

Our Ticagrelor Related Compound 70 Hcl is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical reference materials. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.