Description

2,2-Difluorocyclohexan-1-Ol CAS NO 1546282-70-5 is a fluorinated cyclohexanol derivative, a versatile chiral building block prized for its unique stereochemistry and fluorine substitution. This compound is critical for introducing structural rigidity and modulating the physicochemical properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty chemicals with tailored surface properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including fluorination and ring-opening reactions.

Basic Information

Product Name	2,2-Difluorocyclohexan-1-Ol
CAS No.	1546282-70-5
Molecular Formula	C6H10F2O
Molecular Weight	136.14 g/mol
Synonyms	2,2-Difluorocyclohexanol; 1-Cyclohexanol, 2,2-difluoro-; trans-2,2-Difluorocyclohexanol; cis-2,2-Difluorocyclohexanol; 2,2-Difluoro-1-cyclohexanol; 2,2-Difluorocyclohexyl alcohol; (1R,2R)-2,2-Difluorocyclohexan-1-ol; (1S,2S)-2,2-Difluorocyclohexan-1-ol
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluorocyclohexan-1-Ol is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.