Description

2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine is a high-purity, stereochemically defined organophosphorus compound, serving as a sophisticated chiral building block or ligand in advanced synthetic chemistry. Its value lies in enabling precise stereocontrol and facilitating complex transformations, which are critical for developing high-performance materials and active pharmaceutical ingredients (APIs). This product is essential for research and development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for asymmetric synthesis and catalysis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and antiviral drug candidates.
• Catalyst Ligand: Used as a chiral ligand in transition metal catalysis for asymmetric hydrogenation, cross-coupling, and other enantioselective reactions.
• Agrochemical Synthesis: Employed in the research and development of advanced, stereospecific pesticides and herbicides.
• Material Science Research: Acts as a building block for creating chiral polymers or functional materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and organometallic chemistry within university and corporate laboratories.
• Process Chemistry: Investigated for scale-up in the development of efficient, stereocontrolled manufacturing routes for complex molecules.

Basic Information

Product Name	2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine
CAS No.	1542796-16-6
Molecular Formula	C19H24NO3P
Molecular Weight	345.37 g/mol
Synonyms	(2R,3R)-2-(6-Methoxy-2-pyridyl)-3-tert-butyl-4-methoxy-2,3-dihydro-1,3-benzoxaphosphole; 2,3-Dihydro-2-(6-methoxy-2-pyridinyl)-3-(1,1-dimethylethyl)-4-methoxybenzo[d][1,3]oxaphosphole, (2R,3R)-; (2R,3R)-3-(tert-Butyl)-4-methoxy-2-(6-methoxypyridin-2-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; Chiral Dihydrobenzooxaphosphole Derivative; Chiral Phosphorus Heterocycle; (R,R)-Enantiomer of the Benzoxaphosphole Pyridine Ligand
EINECS	Contact for details

Quality Control

Our 2-((2R,3R)-3-(tert-Butyl)-4-Methoxy-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)-6-Methoxypyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and mass spectrometry for structural confirmation and purity assessment. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.