Description

2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine is a sophisticated chiral organophosphorus compound, serving as a critical intermediate in advanced organic synthesis. Its value lies in its unique stereochemistry and structural framework, which are essential for constructing complex molecules with high enantiomeric purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing chiral drug candidates, particularly in kinase inhibitor and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used in the development of novel phosphorus-based ligands for transition metal-catalyzed reactions.
• Agrochemical Research: Intermediate in the synthesis of advanced, stereospecific pesticides and herbicides.
• Material Science: Component in the research of chiral polymers and advanced organic electronic materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine
CAS No.	1542796-11-1
Molecular Formula	C24H28NO3P
Molecular Weight	409.46 g/mol
Synonyms	(2S,3S)-3-(tert-Butyl)-4-(2,6-dimethoxyphenyl)-2-(pyridin-2-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; 2-[(2S,3S)-3-tert-Butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphol-2-yl]pyridine; (2S,3S)-3-tert-Butyl-4-(2,6-dimethoxyphenyl)-2-(2-pyridyl)-2,3-dihydro-1,3-benzoxaphosphole; Chiral Dihydrobenzooxaphosphole Derivative; tert-Butyl Dihydrobenzooxaphosphole Pyridine Compound
EINECS	Contact for details

Quality Control

Our 2-((2S,3S)-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphol-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.