Description

1-(6-Bromo-2,3-Difluorophenyl)Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its bromo- and difluoro-substituted aromatic ketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the difluorophenyl moiety enhances biological activity and metabolic stability.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its halogenated aromatic core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of tailored compounds for client-specific discovery and development programs.

Basic Information

Product Name	1-(6-Bromo-2,3-Difluorophenyl)Ethanone
CAS No.	1542563-93-8
Molecular Formula	C8H5BrF2O
Molecular Weight	235.03 g/mol
Synonyms	6'-Bromo-2',3'-Difluoroacetophenone; 2',3'-Difluoro-6'-Bromoacetophenone; 1-Acetyl-6-bromo-2,3-difluorobenzene; Ethanone, 1-(6-bromo-2,3-difluorophenyl)-; 6-Bromo-2,3-difluoroacetophenone; 2,3-Difluoro-6-bromoacetophenone; (6-Bromo-2,3-difluorophenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(6-Bromo-2,3-Difluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.