Description

3-Bromo-2,6-Difluorobenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in its unique substitution pattern, which allows for selective functionalization and the introduction of both bromine and fluorine atoms into complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form biaryl structures.
• Fluorination Chemistry Studies: Acts as a model compound for studying the electronic effects of ortho-fluorine substitution on amide reactivity and aromatic systems.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Bromo-2,6-Difluorobenzamide
CAS No.	1541810-83-6
Molecular Formula	C7H4BrF2NO
Molecular Weight	236.02 g/mol
Synonyms	3-Bromo-2,6-difluorobenzamide; 2,6-Difluoro-3-bromobenzamide; Benzamide, 3-bromo-2,6-difluoro-; 1541810-83-6; 3-Br-2,6-F2-Benzamide; 3-Bromo-2,6-difluoro-benzoic acid amide
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,6-Difluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.