Description

1-(2,2-Difluoroethyl)Cyclopropane-1-Carboxylic Acid is a high-value, fluorinated cyclopropane carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both a cyclopropane ring and a difluoroethyl moiety, makes it an essential building block for introducing conformational rigidity and fluorine atoms into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its properties can enhance metabolic stability, bioavailability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorinated cyclopropane structure can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require fluorinated components for specific thermal or chemical resistance properties.
• Fluorine Chemistry Building Block: Essential for exploratory synthesis in academic and industrial labs focused on incorporating fluorine atoms into complex organic frameworks.

Basic Information

Product Name	1-(2,2-Difluoroethyl)Cyclopropane-1-Carboxylic Acid
CAS No.	1541125-74-9
Molecular Formula	C7H10F2O2
Molecular Weight	164.15 g/mol
Synonyms	Cyclopropanecarboxylic acid, 1-(2,2-difluoroethyl)-; 1-(2,2-Difluoroethyl)cyclopropanecarboxylic acid; 1-(Difluoroethyl)cyclopropanecarboxylic acid; 1541125-74-9; 2,2-Difluoroethylcyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(2,2-Difluoroethyl)Cyclopropane-1-Carboxylic Acid adheres to stringent in-process controls and final batch release testing to ensure consistent high purity and reliable performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for verification. Our quality system is designed to meet the exacting standards required for pharmaceutical and advanced chemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.