Description

2-(2-Aminophenyl)-1,1,1-Trifluoro-2-Propanol CAS NO 1535978-10-9 is a specialized fluorinated amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an aromatic amine and a trifluoromethylated alcohol group, makes it a versatile precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where the introduction of fluorine atoms can dramatically alter biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with unique surface properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research exploring the effects of fluorination on molecular behavior.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	2-(2-Aminophenyl)-1,1,1-Trifluoro-2-Propanol
CAS No.	1535978-10-9
Molecular Formula	C9H10F3NO
Molecular Weight	205.18 g/mol
Synonyms	1,1,1-Trifluoro-2-(2-aminophenyl)propan-2-ol; 2-(2-Aminophenyl)-1,1,1-trifluoropropan-2-ol; α-(2-Aminophenyl)-α-(trifluoromethyl)ethanol; 2-Amino-α-(trifluoromethyl)benzenemethanol; 2-(2-Aminophenyl)-2-(trifluoromethyl)ethanol; 1,1,1-Trifluoro-2-(2-aminophenyl)-2-propanol; 2-(2-Aminophenyl)-1,1,1-trifluoro-2-propanol; 2-Amino-α,α,α-trifluoroacetophenone alcohol adduct
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Aminophenyl)-1,1,1-Trifluoro-2-Propanol is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.