Description

(1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarbonitrile is a high-purity chiral cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where the specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a substrate in catalytic reactions to study and induce stereoselectivity.
• Fine Chemical Synthesis: A versatile building block for constructing complex, stereodefined molecular architectures in custom synthesis projects.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological development and process chemistry research.

Basic Information

Product Name	(1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarbonitrile
CAS No.	1535163-09-7
Molecular Formula	C11H11NO
Molecular Weight	173.21 g/mol
Synonyms	(1S,2R)-1-Phenyl-2-(hydroxymethyl)cyclopropanecarbonitrile; (1S,2R)-2-(Hydroxymethyl)-1-phenylcyclopropanecarbonitrile; (1S,2R)-1-Phenyl-2-(hydroxymethyl)cyclopropanenitrile; (1S,2R)-rel-2-(Hydroxymethyl)-1-phenylcyclopropanecarbonitrile; (1S,2R)-1-Phenyl-2-(hydroxymethyl)cyclopropane-1-carbonitrile; Chiral Phenylcyclopropane Carbonitrile Derivative
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-(Hydroxymethyl)-1-Phenylcyclopropanecarbonitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.