Description

Cyclobutaneacetic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its unique cyclobutane ring structure, which is increasingly sought after in medicinal chemistry for its potential to modulate the pharmacokinetic properties of drug candidates. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring constrained molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Peptidomimetic Research: Used to incorporate constrained, non-natural amino acid analogs into peptide chains to enhance stability and biological activity.
• Protease Inhibitor Development: Serves as a core scaffold or side-chain component in the design of inhibitors for various enzymatic targets.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying protein-ligand interactions and cellular pathways.
• Process Chemistry & Scale-up: Supports route scouting and optimization from milligram to kilogram scale for pre-clinical and clinical trial material supply.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.

Basic Information

Product Name	Cyclobutaneacetic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]-
CAS No.	1531669-06-3
Molecular Formula	C14H17NO4
Molecular Weight	263.29 g/mol
Synonyms	1-[(Benzyloxycarbonyl)amino]cyclobutaneacetic acid; Z-1-Aminocyclobutane-1-acetic acid; (1-(((Benzyloxy)carbonyl)amino)cyclobutyl)acetic acid; Cbz-1-Aminocyclobutane-1-acetic Acid; N-Carbobenzoxy-1-aminocyclobutane-1-acetic Acid; 1-Aminocyclobutane-1-acetic acid, N-Cbz-protected; N-Z-1-Aminocyclobutylacetic Acid
EINECS	Contact for details

Quality Control

Every batch of Cyclobutaneacetic Acid, 1-[[(Phenylmethoxy)Carbonyl]Amino]- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.