Description

1,3-Dibromo-2-Fluoro-4-Methoxybenzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing complex halogenated benzene cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the dibromo-fluoro-methoxy motif is critical for bioactivity.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed reactions (e.g., Suzuki, Stille) due to the presence of bromine substituents.
• Fluorine Chemistry: Utilized in studies exploring the effects of fluorine introduction on molecular properties like metabolic stability and lipophilicity.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1,3-Dibromo-2-Fluoro-4-Methoxybenzene
CAS No.	1526600-49-6
Molecular Formula	C7H5Br2FO
Molecular Weight	307.92 g/mol
Synonyms	2-Fluoro-1,3-dibromo-4-methoxybenzene; 4-Methoxy-2-fluoro-1,3-dibromobenzene; 1,3-Dibromo-2-fluoro-4-methoxy-benzene; Benzene, 1,3-dibromo-2-fluoro-4-methoxy-; 1526600-49-6; 2-Fluoro-4-methoxy-1,3-dibromobenzene
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-2-Fluoro-4-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.